A spiropyran-decorated nanocoating for dynamically regulating bacteria/cell adhesion and detachment
作者
Li, J (Li, Jie) [1] ; Ma, Z (Ma, Zhuang) [1] ; Li, AR (Li, Anran) [1] ; Huang, SY (Huang, Siyuan) [1] ; Zhang, YF (Zhang, Yufei) [1] ; Xue, Y (Xue, Yun) [1] ; Song, XH (Song, Xianhui) [1] ; Zhang, Y (Zhang, Ye) [1] ; Hong, SH (Hong, Shihao) [1] ; Wang, M (Wang, Mo) [4] ; Wu, ZM (Wu, Zhongming) [2] , [3] ; Zhang, XE (Zhang, Xinge) [1]
出版时间
OCT 11 2023
已索引
2023-10-14
文献类型
Article
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摘要
Microorganism adhesion and the resulting contamination of the biomaterial is one of the major causes of biomedical device failure. Stimuli-responsive materials based on dynamically regulating interactions with reversible characteristics of on-off states have attracted increasing attention. Here, a facile self-assembled biomaterial nanocoating constructed using acidity- and photoregulated spiropyran-modified nanoparticles was developed for reversibly regulating bacteria or mammalian cell adhesion-and-detachment. The coating was formed by coating a solution of spiropyran-conjugated nanoparticles around the surface of a silica gel followed by curing and drying at 60 degrees C for 30 min. Importantly, efficient adhesion-and-detachment of bacteria or cells could be controlled even after 8 cycles owing to the excellent acidity- and light-switched ability. Collectively, this well-defined self-assembled nanocoating as a dynamical and reversible agent provides promising insight for the development of biomedical devices, especially for biomaterial medical coatings.
A facile self-assembled biomaterial nanocoating constructed using acidity- and photoregulated spiropyran-modified nanoparticles was developed for reversibly regulating bacteria or mammalian cell adhesion-and-detachment.