A heteromultivalent host-guest sensor array for cell recognition and discrimination
作者:
Hu, XY (Hu, Xin-Yue) [1] ;
Hu, ZY (Hu, Zong-Ying) [1] ;
Tian, JH (Tian, Jia-Hong) [1] ;
Shi, L (Shi, Lin) [1] ;
Ding, F (Ding, Fei) [1] ;
Li, HB (Li, Hua-Bin) [1] ;
Guo, DS (Guo, Dong-Sheng) [1]
CHEMICAL COMMUNICATIONS, 2022
摘要
We present a supramolecular sensor array based on a series of heteromultivalent macrocyclic coassemblies using amphiphilic calixarenes and cyclodextrin as the building blocks for cell recognition. The corresponding cross-reactivity between the coassemblies and cells served as the unique fingerprint for cell classification, and successfully identified the normal cell lines, cancerous cell lines, and cross-contaminated cells.