Photosensitizer-AgNP composite with an ability to selectively recognize pathogen and enhanced photodynamic efficiency

Zhang, JQ (Zhang, Jiaqi)^[ 1 ] ; Lu, ZT (Lu, Zhentan)^[ 1 ] ; Yu, ZG (Yu, Zhenguo)^[ 1 ] ; Zhong, WB (Zhong, Weibing)^[ 1,2 ] ; Jiang, HQ (Jiang, Haiqing)^[ 1 ] ; Zhao, QH (Zhao, Qinghua)^[ 1 ] ; Li, F (Li, Fei)^[ 1 ] ; Zhang, XG (Zhang, Xinge)^[ 3 ] ; Wang, D (Wang, Dong)^[ 1,2 ]

NEW JOURNAL OF CHEMISTRY, 2017, 41(21): 12371-12374

DOI: 10.1039/c7nj02204b

 WOS:000413526200002

Abstract

BODIPY-functionalized glycopolymer-modified AgNPs were prepared as a PDT agent. The agent was "smart'', i.e., it could distinguish pathogens from normal cells, and showed a photodynamic efficiency three times greater than that of free photosensitizer under the same light intensity. The work is a good attempt to make a new generation of PDT agents for antibacterial applications.