功能高分子材料教育部重点实验室

生物医用高分子
郭术涛
博士,研究员,博士生导师,中组部“青年千人”
联系电话:022-83662785
E-mail:stguo@nankai.edu.cn
通讯地址:天津市南开区卫津路94号蒙民伟楼310,邮编300071
  • 学习和工作经历

    2014-2016   哈佛医学院/麻省理工学院,博士后

    2011-2014   北卡罗来纳大学教堂山分校,药学院,博士后

    2008/032010/12,天津大学,化工学院高分子系,博士

    2006/092010/12,天津大学,化工学院高分子系,硕士

    2002/092006/07,天津大学,化工学院高分子系,学士

  • 研究方向

    医用高分子设计与合成,天然可降解高分子改性,脂质体,微/纳米制剂制备与评价

  • 部分主持项目

    “青年千人计划”项目

  • 科研成果

    在Journal of the American Chemical Society, Science Translational Medicine, ACS Nano, Nature Communications, Nano Letters, Advanced Functional Materials 等杂志发表论文41篇,SCI引用980余次。中国授权发明专利4项,申请5项美国发明专利。

  • 代表论文
    1.  Guo, S., Nakagawa, Y., Barhoumi, A., Wang, W., Zhan, C., Tong, R., Santamaria, C., & Kohane, D. S. (2016). Extended release of native drug conjugated in polyketal microparticles. Journal of the American Chemical Society, 138(19), 6127-6130.
    2.  Guo, S., Lin, C. M., Xu, Z., Miao, L., Wang, Y., & Huang, L. (2014). Co-delivery of cisplatin and rapamycin for enhanced anticancer therapy through synergistic effects and microenvironment modulation. ACS Nano, 8(5), 4996-5009.
    3.  Guo, S., Miao, L., Wang, Y., & Huang, L. (2014). Unmodified drug used as a material to construct nanoparticles: Delivery of cisplatin for enhanced anti-cancer therapy. Journal of Controlled Release, 174, 137-142.
    4.  Guo, S., & Huang, L. (2014). Nanoparticles containing insoluble drug for cancer therapy. Biotechnology Advances, 32(4), 778-788.
    5.  Guo, S., Wang, Y., Miao, L., Xu, Z., Lin, C. M., Zhang, Y., & Huang, L. (2013). Lipid-coated cisplatin nanoparticles induce neighboring effect and exhibit enhanced anticancer efficacy. ACS Nano, 7(11), 9896-9904.
    6.  Guo, S., Huang, Y., Zhang, W., Wang, W., Wei, T., Lin, D., Xing, J., Deng, L., Du, Q., Liang, Z., Liang, X.-J., & Dong, A. (2011). Ternary complexes of amphiphilic polycaprolactone-graft-poly (n,n-dimethylaminoethyl methacrylate), DNA and polyglutamic acid-graft-poly(ethylene glycol) for gene delivery. Biomaterials, 32(18), 4283-4292.
    7.  Guo, S., Huang, Y., Jiang, Q., Sun, Y., Deng, L., Liang, Z., Du, Q., Xing, J., Zhao, Y., Wang, P. C., Dong, A., & Liang, X.-J. (2010). Enhanced gene delivery and sirna silencing by gold nanoparticles coated with charge-reversal polyelectrolyte. ACS Nano, 4(9), 5505-5511.